We're enrolling autistic children ages 4-7 yrs. to participate in our Duke Autism HERO study, with an aim to build a deeper understanding of brain development and the overlap between autism, ADHD, and anxiety. What we learn could lead to potential new interventions or treatments for children on the spectrum. Our Duke Autism HERO participants will receive an official "Duke Research Superhero" certificate to take home to show their friends, family, and teachers.

This is a phase II randomized (flip of a coin), blinded, placebo-controlled clinical trial testing whether an IV infusion of hCT-MSCs helps decrease symptoms of Autism in young children. All participants will receive 2 IV infusions given six months apart. One infusion will be hCT-MSCs, and one will be an inactive placebo product. Participants and families will not know the order in which the products are given. Participant reimbursement will be provided after the baseline visit and the one year remote visit. Initial requirements*: